Michael Lazarus Selected Research

Prostaglandin D2

12/2020	Niacin ameliorates ulcerative colitis via prostaglandin D2 -mediated D prostanoid receptor 1 activation.
10/2020	Niacin Attenuates Pulmonary Hypertension Through H-PGDS in Macrophages.
1/2020	DP1 Activation Reverses Age-Related Hypertension Via NEDD4L-Mediated T-Bet Degradation in T Cells.
1/2019	L-PGDS-produced PGD2 in premature, but not in mature, adipocytes increases obesity and insulin resistance.
1/2017	Niacin Promotes Cardiac Healing after Myocardial Infarction through Activation of the Myeloid Prostaglandin D2 Receptor Subtype 1.
1/2017	Niacin ameliorates ulcerative colitis via prostaglandin D2-mediated D prostanoid receptor 1 activation.
7/2015	The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep.
3/2014	Prostaglandin D(2) is crucial for seizure suppression and postictal sleep.

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Michael Lazarus Research Topics

Disease

4	Fever (Fevers) 07/2015 - 04/2006
3	Vascular Remodeling 10/2020 - 07/2013
3	Pain (Aches) 01/2020 - 02/2009
3	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2019 - 01/2014
3	Inflammation (Inflammations) 01/2017 - 02/2009
2	Ulcerative Colitis 12/2020 - 01/2017
2	Pulmonary Hypertension 10/2020 - 03/2015
2	Hypoxia (Hypoxemia) 10/2020 - 03/2015
2	Infections 11/2019 - 07/2011
2	Sleep Wake Disorders 01/2019 - 01/2019
2	Flushing 01/2017 - 01/2017
2	Myocardial Infarction 01/2017 - 01/2017
2	Fistula 01/2013 - 08/2011
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022
1	Narcolepsy 12/2021
1	Mania (Manias) 06/2020
1	Ataxia (Dyssynergia) 01/2020
1	Epilepsy (Aura) 01/2020
1	Hyperalgesia 01/2020
1	Hypertension (High Blood Pressure) 01/2020
1	Intellectual Disability (Idiocy) 01/2020
1	Neuralgia (Stump Neuralgia) 01/2020
1	Sleep Deprivation 01/2020
1	Neoplasms (Cancer) 11/2019
1	Body Weight (Weight, Body) 01/2019
1	Insulin Resistance 01/2019
1	Obesity 01/2019
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2019
1	Peritonitis 01/2017
1	Colitis 01/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2017
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2017
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2017
1	Disorders of Excessive Somnolence (Hypersomnia) 01/2017
1	Seizures (Absence Seizure) 03/2014
1	Hyperplasia 07/2013
1	Neointima 07/2013
1	Sepsis (Septicemia) 01/2013

Drug/Important Bio-Agent (IBA)

8	Prostaglandin D2IBA 12/2020 - 03/2014
7	ProstaglandinsIBA 01/2022 - 02/2009
4	Niacin (Nicotinic Acid)FDA LinkGeneric 12/2020 - 01/2017
4	Dinoprostone (PGE2)FDA Link 02/2016 - 04/2006
3	Pharmaceutical PreparationsIBA 12/2021 - 01/2017
2	Modafinil (Provigil)FDA Link 12/2021 - 01/2020
2	MonocrotalineIBA 10/2020 - 03/2015
2	Dopamine (Intropin)FDA LinkGeneric 06/2020 - 02/2016
2	CytokinesIBA 01/2020 - 01/2017
2	Caffeine (No Doz)FDA LinkGeneric 01/2019 - 07/2011
2	CholesterolIBA 01/2019 - 01/2017
2	LipopolysaccharidesIBA 02/2009 - 04/2006
1	sulprostoneIBA 01/2022
1	Therapeutic UsesIBA 10/2020
1	Semaxinib (SU5416)IBA 10/2020
1	prostaglandin R2 D-isomerase (prostaglandin D2 synthase)IBA 10/2020
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 10/2020
1	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 06/2020
1	Analgesics (Analgesic Drugs)IBA 01/2020
1	HydroxylysineIBA 01/2020
1	Indicators and Reagents (Reagents)IBA 01/2020
1	InterferonsIBA 01/2020
1	Lysine (L-Lysine)FDA Link 01/2020
1	Reserpine (Serpasil)FDA Link 01/2020
1	Scopolamine (Hyoscine)FDA Link 01/2020
1	Superoxides (Superoxide)IBA 01/2020
1	Tryptophan (L-Tryptophan)FDA Link 01/2020
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020
1	Cholinergic Agents (Cholinergics)IBA 11/2019
1	AdiponectinIBA 01/2019
1	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 01/2019
1	Purinergic P1 Receptors (Adenosine Receptor)IBA 01/2019
1	Fatty Acid-Binding ProteinsIBA 01/2019
1	Adenosine (Adenocard)FDA LinkGeneric 01/2019
1	Triglycerides (Triacylglycerol)IBA 01/2019
1	ParvalbuminsIBA 12/2017
1	Designer DrugsIBA 12/2017
1	prostaglandin D2 receptorIBA 01/2017
1	Sulfonic AcidsIBA 01/2017
1	sym-trinitrobenzeneIBA 01/2017
1	ZymosanIBA 01/2017
1	Dextran SulfateIBA 01/2017
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2017
1	MK-0524IBA 01/2017
1	gamma-Aminobutyric Acid (GABA)IBA 02/2016
1	CopperIBA 10/2015
1	IronIBA 10/2015
1	Divalent CationsIBA 10/2015
1	ManganeseIBA 10/2015
1	Protein Isoforms (Isoforms)IBA 03/2015
1	Pentylenetetrazole (Metrazol)IBA 03/2014
1	Zolpidem (Ambien)FDA LinkGeneric 01/2014
1	RacloprideIBA 01/2014
1	CorticosteroneIBA 01/2014
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 07/2013
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 07/2013
1	Monomeric GTP-Binding ProteinsIBA 07/2013
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 07/2013

Therapy/Procedure

4	Therapeutics 01/2017 - 08/2011
2	Ligation 01/2020 - 01/2017
1	Catheters 01/2013